Knoevenagel reaction

noun

Knoe·​ve·​na·​gel reaction

kəˈnə(r)vəˌnāgəl-,

kəˈnə̄v-

variants or Knoevenagel condensation

: an aldol-type condensation catalyzed by amines that takes place between an aldehyde or ketone and a compound containing an active methylene group (as in esters of acetoacetic acid, malonic acid, or cyanoacetic acid)

Word History

Etymology

after Emil Knoevenagel †1921 German chemist

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